Antibodies (IgG, IgM, or IgA) that interfere with one or more in vitro phospholipid dependent coagulation reactions. Due to their heterogeneity no single laboratory test is capable of identifying every LA. LA are grouped into a family of antibodies known as antiphospholipid antibodies. Non-transitory LAs are usually associated with an increased risk for venous and arterial thrombosis.
