Antithrombin activity

CompanyReagentLink to informationRemarks
ChromogenixCoamatic AntithrombinReagent: Lyophilized

Method: Chromogenic


Assay principle: Anti Xa

ChromogenixCoamatic LR AntithrombinReagent: Liquid

Method: Chromogenic


Assay principle: Anti Xa

Helena BiosciencesAntithrombin XaReagent: Lyophilized

Method: Chromogenic


Assay principle: Anti Xa

Hyphen BioMed Biophen AntithrombinHyphen Biophen Antithrombin Reagent: Lyophilized

Method: Chromogenic


Assay principle: Anti Xa


Interferences: No interference of heparin, heparin Cofactor II, alpha-2-macroglobulin or alpha1-Antitrypsin.No significant interference for haemoglobin < 2.5 mg/ml, and bilirubin < 0.1 mg/ml

Hyphen BioMedBiophen AT anti-(h)-Xa LRTHyphen Biophen AT anti-(h)-Xa LRTReagent: Liquid

Method: Chromogenic


Assay principle: Anti Xa


Interferences: No interference of heparin, heparin Cofactor II, alpha-2-macroglobulin or alpha1-Antitrypsin.No significant interference for haemoglobin < 2.5 mg/ml, and bilirubin < 0.1 mg/ml

Hyphen BioMed Biophen AT (anti-lla)Hyphen Biophen AT (anti-lla)Reagent: Lyophilized

Method: Chromogenic


Assay principle: Anti IIa


Interferences: No interference of heparin (UFH, LMWH) at usual therapeutic doses

Hyphen BioMed Biophen AT (LRT)Hyphen Biophen AT (LRT)

Reagent: Liquid


Method: Chromogenic


Assay principle: Anti Xa


Interferences: No interference of heparin, heparin Cofactor II, alpha-2-macroglobulin or alpha1-Antitrypsin.No significant interference for haemoglobin < 2.5 mg/ml, and bilirubin < 0.1 mg/ml


Nordic BiomarkerMRX Antithrombin

Reagent: Liquid


Method: Chromogenic


Assay principle: Anti Xa


RenamReachrom-ATIII

Method: Chromogenic


RenamReaclot-ATIII

Method: Clotting


RocheATRoche AT

Reagent: Liquid


Method: Chromogenic


Assay principle: anti IIa


Siemens Healthineers Berichrom Antithrombin IIISiemens Berichrom Anthitrombin III

Reagent: Lyophilized


Method: Chromogenic


Assay principle: Anti Xa


Inteferences: Therapeutic doses of hirudin or other direct thrombin inhibitors will cause erroneously

increased antithrombin III activity.


Siemens Healthineers Innovance AntithrombinSiemens Innovance Antithrombin

Reagent: Liquid


Method: Chromogenic


Assay principle: Anti Xa


Interferences: No interference of heparin < 2 U/ml, heparin cofactor II < 400 mg/L, hirudin < 5 mg/L, therapeutic doses of oral direct factor Xa inhibitors may cause erroneously increased

antithrombin activity.


Stago STA-Stachrom AT IIIStago STA-Stachrom AT III

Reagent: Lyophilized


Method: Chromogenic


Assay principle: Anti IIa


Interferences: No interferences of therapeutic doses of heparin, hemoglobin < 7 g/l, bilirubin < 200 mg/l,

triglycerides < 7.6 g/l, thrombin inhibitors may lead to an over-estimation of the AT level.


Stago, TcoagTriniCHROM Antithrombin llaStago TriniCHROM Antitrombin IIa

Method: Chromogenic


Assay principle: Anti IIa


Interferences: Interference of heparin cofactor


Stago, TcoagTriniCHROM Antithrombin XaStago TriniCHROM Antitrombin Xa

Method: Chromogenic


Assay principle: Anti Xa


Interferences: No interference of heparin cofactor II


TechnocloneTechnochrom ATIII kitTechnoclone Technochrom ATIII kitMethod: Chromogenic

Assay principle: Anti IIa

TechnocloneTechnochrom ATIII manual method kitTechnoclone Technochrom ATIII manual method kitMethod: Chromogenic

Assay principle: Anti IIa

WerfenHemosIL AntithrombinWerfen HemosIL Antithrombin

Reagent: Lyophilized


Method: Chromogenic


Assay principle: Anti Xa


Interferences: No interference of  (UF heparin or LMW

heparin) < 2 U/mL, α1-Antitrypsin < 2 mg/mL, α2-macroglobulin< 7 mg/mL, Heparin

Cofactor II < 3 IU/mL, hemoglobin < 200 mg/dL, bilirubin < 20 mg/dL and triglycerides <

1000 mg/dL.


WerfenHemosIL liquid AntithrombinWerfen HemosIL liquid Antithrombin

Reagent: Liquid


Method: Chromogenic


Assay principle: Anti Xa


Interferences: No interference of heparin (UF heparin or LMW

heparin) < 4 U/mL, α1-Antitrypsin < 4 mg/mL, α2-macroglobulin < 7 mg/mL, Heparin

Cofactor II < 4 U/mL, hemoglobin < 150 mg/dL, bilirubin < 40 mg/dL and triglycerides <

500 mg/dL.


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