An agent that prevents coagulation of blood or blood products. Sodium citrate is the anticoagulant of choice for samples (blood becomes hypocalcemic) used in coagulation testing. Pharmacological anticoagulants such as coumarin derivatives, heparin, LMWH, and hirudin are used in the prophylaxis and treatment of thrombotic disorders. The body also has naturally occurring anticoagulants (Antithrombin and Activated Protein C).
