Activated protein C resistance ratio

CompanyReagentLink to informationRemarks
BioMedica diagnosticsACTICLOT Protein C Resistance

Method: Clotting


Activator: Russell’s viper venom factor V dependent prothrombin activator


Interferences:  No interference of UFH, LMWH and pentasaccharide


FV deficient plasma: No


ChromogenixCoatest APC Resistance

Method: Clotting


Activator: activated protein C and calcium


FV deficient plasma: No


ChromogenixCoatest APC Resistance V

Method: Clotting


Assay principle: activated protein C and calcium


Interferences: No interference of heparin or oral anticoagulant therapy


FV deficient plasma: Yes


DiagenPCA kit

Method: Clotting


Activator: Snake venom agkistrodon contortrix


FV deficient plasma: Yes and No


Helena BiosciencesPCA Ratio Kit

Method: Clotting


Acivator: activated protein C and calcium


FV deficient plasma: Yes


ImmBioMedOLIGOBIND APC activity assay

Method: EIA


FV deficient plasma: No


Hyphen BioMedHemoclot Quanti V-LHyphen Hemoclot Quanti V-L

Method: Clotting


Activator: Factor Xa in presence of phospholipids and calcium


FV deficient plasma: Yes


PentapharmPefakit APC-R Factor V LeidenPenthapharm Pefakit APC-R FVL

Method: Clotting


Activator: A snake venom factor Va dependent prothrombin activator


Interferences: No interference of UFH, LMWH and pentasaccharide


FV deficient plasma: No


RenamReaPrC/FV

Method: Clotting


Activator: Activated protein C and calcium


FV deficient plasma: Yes


Roche APC ResistanceRoche APC Resistance

Method: Clotting


FV deficient: No


Siemens HealthineersProC Ac RSiemens ProC Ac R

Method: Clotting


Activator: Snake venom agkistrodon contortrix


FV deficient plasma: No


Siemens HealthineersProC Global +/- FVSiemens ProC global

Method: Clotting


Activator: Snake venom agkistrodon contortrix


Interferences: No interference of heparin up to 0.8 U/mL, (Without factor V deficient plasma sensitive to deficiencies of factor V Leiden, proteine C and S, certain lupus anticoagulants and high factor VII levels)


FV deficient plasma: Yes


Stago STA-Staclot APC-RStago STA-Staclot APC-R

Method: Clotting


Activator: Crotalus viridis helleri venom


Interferences: Interference of low Factor V (<50%) and thrombin inhibitors, no interference of heparin up to 1.0 U/mL.


FV deficient plasma: Yes


TechnocloneAPC Resistance kitTechnoclone APC Resistance kit

Method: Clotting


Activator: A snake venom factor Va dependent prothrombin activator


Interferences: Interference of low Factor V (<50%) and thrombin inhibitors, no interference of heparin up to 2.0 U/mL and Lupus


FV deficient plasma: No


WerfenHemosIL Factor V Leiden (APCR)Werfen HemosIL Factor V Leiden

Method: Clotting


Activator: Activated protein C and calcium


Interferences: No interference of heparin up to 1 U/mL and oral anticoagulant therapy


FV deficient plasma: Yes


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