Protein C activity

CompanyReagentLink to informationRemarks
BioMedica DiagnosticsACTICLOT C

Method: Clotting


Activator: Derived from the venom of the viper agkistrodon contortrix


ChromogenixCoamatic Protein C

Method: Chromogenic


Activator: Derived from the venom of the viper agkistrodon contortrix


Interferences: No interference of heparin levels up tot 3 IU/ml


Helena BiosciencesProtein C

Method: Chromogenic


Activator: Derived from the venom of the viper agkistrodon contortrix


Hyphen BioMed Biophen Protein C LRTHyphen Biophen Protein C LRT

Method: Chromogenic


Activator: Derived from the venom of the viper agkistrodon contortrix


Interferences: No interference for heparin <  1 IU/mL, bilirubin < 60 mg/dL, hemoglobin < 500 mg/dL and intralipids concentration < 1000 mg/dL. Aprotinin or presence of anti-human Protein C antibodies may decrease the measured Protein C activity.


Hyphen BioMed Biophen Protein CHyphen Biophen Protein C 5

Method: Chromogenic


Activator: Derived from the venom of the viper agkistrodon contortrix


Interferences: No interference for heparin <  1 IU/mL, bilirubin < 60 mg/dL, hemoglobin < 500 mg/dL and intralipids concentration < 1000 mg/dL. Aprotinin or presence of anti-human Protein C antibodies may decrease the measured Protein C activity.


Hyphen BioMedHemoclot Protein CHyphen Hemoclot Protein C

Method: Clotting


Activator: Derived from the venom of the viper agkistrodon contortrix


Interferences: No interference for heparin <  1 IU/mL. Special caution should be taken for patients with known high levels of FVIII:C or with LA


Nordic BiomarkerMRX Protein C

Method: Chromogenic


Activator: Protein C activator


Interferences:  No interference from heparin < 2 U/ml, bilirubin ≤20 mg/dL, haemoglobin ≤200 mg/dL, triglycerides ≤350 mg/dL


PentapharmProtacProtac

Method: Chromogenic and clotting


Activator: Derived from the venom of the viper agkistrodon contortrix


Precision BiologicCryocheck Clot CPrecision Biologic Cryocheck Clot C

Method: Clotting


Activator: Russell’s viper venom (RVV-X)


Interferences: No interference of factor VIII:C activity levels < 600% and heterozygous factor VLeiden mutation


RenamReachrom protein C

Method: Chromogenic


RocheProtein C ChromRoche Protein C Chrom

Method: Chromogenic


Activator: Snake venom


Siemens Healthineers Berichrom Protein CSiemens Berichrom Protein C

Method: Chromogenic


Activator: Derived from the venom of the viper agkistrodon contortrix


Interferences: False low protein C activity may be obtained in patients being treated with aprotinin


Siemens HealthineersProtein C ReagentSiemens Protein C Reagent

Method: Clotting


Activator: Derived from the venom of the viper agkistrodon contortrix


Interferences: False low protein C activity may be obtained in patients being treated with aprotinin.


StagoSTA_Stachrom Protein CStago STA Stacrom Protein C

Method: Chromogenic


Activator: Derived from the venom of the viper agkistrodon contortrix


Interferences: No interference from hemoglobin <

2 g/l, bilirubin < 200 mg/l and triglycerides < 4 g/l.


StagoSTA-Staclot Protein CStago STA-Staclot Protein C

Method: Clotting


Activator: Derived from the venom of the viper agkistrodon contortrix


Interferences: No interference from heparin < 1 U/ml, LA,  factor VIII:C activity levels < 250%. Trombin inhibitors may interference


Stago, TcoagTriniCLOT Protein C IIStago TriniCLOT Protein C II

Method: Clotting


Activator: Derived from the venom of the viper agkistrodon contortrix


Technoclone Technochrom Protein CTechnoclone Technochrom Protein C

Method: Chromogenic


Activator: Derived from the venom of the viper agkistrodon contortrix


Interferences: No interference from heparin < 2 U/ml


Technoclone Technoclot Protein CTechnoclone Technoclot Protein C

Method: Clotting


Activator: Derived from the venom of the viper agkistrodon contortrix


WerfenHemosIL ProclotWerfen HemosIL ProClot

Method: Clotting


Activator: Derived from the venom of the viper agkistrodon contortrix


Interferences: No interference from heparin (LMW) up to 0.7 U/mL,  heparin (UF) up to 1.5 U/mL, hemoglobin < 200 mg/dL, bilirubin < 25 mg/dL and triglycerides < 600 mg/dL.

Protein C results may be affected by LA and high levels of factor VIII (>250%) and APC-R


WerfenHemosIL Protein CWerfen  HemosIL Protein C

Method: Chromogenic


Activator: Derived from the venom of the viper agkistrodon contortrix


Interferences: no interference from heparin (UF or LMW heparin) < 2 U/mL,

hemoglobin < 200/500 mg/dL, triglycerides < 500/890 mg/dL and bilirubin 5/ 21 mg/dL. ACL Classic/ACL TOP.


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